Hi, if anyone can correct me where i'm going wrong with transduction pathways of neurotransmitters and hydrophilic signals that would be greatly appreciated
Neurotransmitters-
Sodium ions diffuse into neuron, potassium ions diffuse out creating the action potential that drives the electrical signal across the neuron
Calcium ions enter axon terminal
Vesicle containing neurotransmitters are stimulated by electrical impulse to move toward the plasma membrane and exocytose the neurotransmitters out of the axon terminal into the synaptic cleft
The neurotransmitters attach to complementary receptors on the post-synaptic neuron and diffuse into the neuron, repeating the process again
Hydrophilic signalling molecules-
bind to complementary plasma membrane receptor on target cell
This activates the intracellular part of the receptor to activate an enzyme in the plasma membrane that catalyses production of the second messenger molecule. Second messenger molecule activates the first enzyme of the enzyme cascade, that then activates the next enzyme and this repeats to amplify the signal until it reaches the nucleus where the specific cellular response occurs (like synthesis of a specific protein)