I have answered this question before, so I will just post my response:
Quite a difficult question. What it is asking is why the difference of 77 nucleotides would be the minimum amount of mutations that have occurred. Over time, the mtDNA will undergo mutations. e.g going from ACACTG to ACATTG, but another mutation may occur reversing the initial mutation, ACATTG back to ACACTG, so the mtDNA may have had more mutations than the 77 different nucleotides, therefore 77 differences, which have been observed can be said to be the minimum (as more mutations may have occurred but they can't be detected).
Whilst we can observe that 77 is the number of base differences, many more substitutions may have occurred but subsequent changes may have reserved the changes, which we cannot determine.