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June 25, 2019, 09:34:09 pm

Author Topic: Signalling Molecules  (Read 472 times)  Share 

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Gianni Farfaglia

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Re: Signalling Molecules
« Reply #15 on: May 18, 2019, 10:44:44 am »
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Why are some cancers resistant to the radiation and chemical treatments that would kill healthy cells.

Thanks in advance.

Bellatrix Lestrange  ;)  ;)  ;)

Hi Bellatrix, there might be many reasons why some cancers are radiation resistant. I don't think at  a VCE level we really have to explore too much the specifics why this might be the case. However a way in VCE context you might think about it is there may be possible dysfunction of certain signalling molecules involved in the cells intrinsic apoptotic pathway and as a result DNA damaging radiation which otherwise may have triggered cell apoptosis may not cause apoptosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914062/
here's a review paper exploring some of the ideas involved for interest but really from a VCE perspective just focus on my point above.