Can someone please check if the following explanation of defence against bacteria is correct?
If bacteria has entered through a cut on the skin, then mast cells lining the blood vessel will release histamine which will dilate nearby blood vessels and also make the blood vessel more permeable to leukocytes including macrophages, neutrophils, eosinophils and basophils.
The phagocytic leukocytes which include macrophages, neutrophils and eosinophils will engulf the bacteria and the neutrophils will perish due to their inability to form new lysosomes hence resulting in pus. Basophils release more histamine and also heparin to prevent blood from clotting in the blood vessels. This leads to inflammation. Finally, platelets will release chemicals or clotting factors which will eventually lead to the formation of fibrin which will form a clot with its fibres over the wound.
I was also wondering, how do the blood vessels return to their original state (from dilation)- in other words, what happens to the histamine once it has performed its function and is no longer needed?
Thanks!