Hi everyone,
Would love some help with these few questions about the immune system...
1. Do Helper T cells and Cytotoxic T cells have receptors
specific to foreign antigens or are the simply specific to the MHC I/MCH II markers on the cell surface? Eg. in order to bind to cell MHC I marker, recognise it as foreign and stimulate apoptosis, does a cytotoxic T cell need a receptor specific to this antigen?
2. I know that once Helper T cells find an antigen they are specific to, that they release interleukins causing them to proliferate themselves and B-cells/Cytotoxic T cells. However, for the activation of either the B cells or Cytotoxic T cells, does the B cell/Cytotoxic T cell first need to bind to the foreign antigen and then the interleukins stimulate their proliferation?
I hope it isn't too hard to understand what I'm trying to ask. Once again thanks for all your help