How much should we know about apoptosis? Is this enough information
Signal molecule binds to death receptor on the cell membrane
This triggers a signal transduction pathway with the activation of caspase proteins
Caspases cleave certain parts of the cell which causes blebbing
Apoptosis is a genetically controlled, programmed cell death that can be initiated by internal and external signals.
It occurs in:
- healthy cells that are no longer needed
- damaged cells and those no longer functioning normally
- immune cells that damage self cells
You should be able to distinguish it from necrosis, which is a non-programmed death of a cell that releases dangerous chemicals into its surroundings and harms neighbouring cells.
I don't think we need to know how apoptosis is initiated.
Can someone please explain the role of the lymphatic system/lymph nodes in immunity?
Lymph nodes are small masses of lymph tissue that are dense with white blood cells, and are found along lymph vessels
(basically what cosine said)